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Intercellular signaling in development and disease / editors-in-chief, Edward A. Dennis, Ralph A. Bradshaw.

Contributor(s): Material type: TextTextPublication details: Amsterdam ; Boston : Academic Press, 2011.Description: xvi, 532 p. : ill. (some col.) ; 28 cmISBN:
  • 9780123822154 (alk. paper)
Subject(s): DDC classification:
  • 571.7/4 22
LOC classification:
  • QP517.C45 INT 2011
NLM classification:
  • QU 375
Summary: "Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
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Item type Current library Call number Copy number Status Barcode
Books in General collection Books in General collection Mzuzu University Library and Learning Resources Centre QP 517.C45 INT 2011 (Browse shelf(Opens below)) 017553 Available mZulm-017553

Includes bibliographical references and index.

"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.

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