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Skin sensitization in chemical risk assessment.

Contributor(s): Material type: TextTextSeries: Harmonization Project document ; no. 5.Publication details: Geneva, Switzerland : World Health Organization, c2008.Description: iv, 85 p. : ill. ; 30 cmISBN:
  • 9789241563604
  • 9241563605
Subject(s): LOC classification:
  • TD 196.45 ski 2008
Online resources: Available additional physical forms:
  • Also available online.
Partial contents:
Skin sensitization in chemical risk assessment : report of a WHO/IPCS international workshop focusing on dose-response assessment / H. Van Loveren, ... [et al.].
Summary: This publication presents the conclusions of an IPCS Workshop on Skin Sensitization in Chemical Risk Assessment. The workshop focused on the question of methods for dose-response assessment, to evaluate the relative ability of a chemical to induce sensitization in the skin, and hence inform risk assessment for humans. In addition this publication includes a series of short articles on this topic by leading experts in the field. The conclusions of the workshop cover such aspects as the nature and utility for risk assessment of the data produced by non-animal test methods (such as quantitative structure-activity relationships), in vitro testing approaches, animal test methods, and epidemiological studies. While traditional animal test methods used for identification and regulation of skin sensitizers have focused on determining whether or not a substance is a sensitizer, this report describes the use of tests for deriving more informative potency information.--Publisher's description.
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Item type Current library Call number Copy number Status Barcode
Books in General collection Books in General collection Mzuzu University Library and Learning Resources Centre TD 196 SKI 2008 (Browse shelf(Opens below)) 003639 Available mZulm-003639

"IPCS International Programme on Chemical Safety"--Cover.

"This project was conducted within the IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals."

"Published under the joint sponsorship of the World Health Organization, the International Labour Organization and the United Nations Environment Programme, and produced within the framework of the Inter-Oganization Programme for the Sound Management of Chemicals."

Includes bibliographical references.

Skin sensitization in chemical risk assessment : report of a WHO/IPCS international workshop focusing on dose-response assessment / H. Van Loveren, ... [et al.].

This publication presents the conclusions of an IPCS Workshop on Skin Sensitization in Chemical Risk Assessment. The workshop focused on the question of methods for dose-response assessment, to evaluate the relative ability of a chemical to induce sensitization in the skin, and hence inform risk assessment for humans. In addition this publication includes a series of short articles on this topic by leading experts in the field. The conclusions of the workshop cover such aspects as the nature and utility for risk assessment of the data produced by non-animal test methods (such as quantitative structure-activity relationships), in vitro testing approaches, animal test methods, and epidemiological studies. While traditional animal test methods used for identification and regulation of skin sensitizers have focused on determining whether or not a substance is a sensitizer, this report describes the use of tests for deriving more informative potency information.--Publisher's description.

Also available online.

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