000			02276cam a2200337 a 4500
001			16617627
005			20180323092012.0
008			110113s2011 ne a b 001 0 eng
010			_a 2011001763
020			_a9780123822154 (alk. paper)
035			_a(DNLM)101551450
040			_aDNLM/DLC _cDLC _dDLC
042			_apcc
050	0	0	_aQP517.C45 _bINT 2011
060	1	0	_aQU 375
082	0	0	_a571.7/4 _222
245	0	0	_aIntercellular signaling in development and disease / _ceditors-in-chief, Edward A. Dennis, Ralph A. Bradshaw.
260			_aAmsterdam ; _aBoston : _bAcademic Press, _c2011.
300			_axvi, 532 p. : _bill. (some col.) ; _c28 cm.
504			_aIncludes bibliographical references and index.
520			_a"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
650		0	_aCellular signal transduction.
650		0	_aCell interaction.
650	1	2	_aSignal Transduction.
650	2	2	_aCell Communication.
700	1		_aDennis, Edward A.
700	1		_aBradshaw, Ralph A., _d1941-
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2lcc _cBK
999			_c13862 _d13862